Microfluidic Affinity Analysis and Hepatitis C Target

September 3, 2008 at 3:36 pm Leave a comment

Stanford University researchers have used microfluidic affinity analysis to discover that an already approved drug in humans, clemizole hydrochloride, hinders RNA binding by the transmembrane protein, NS4B, in Hepatitis C virus (HCV).  Read the Stanford School of Medicine’s press release here.  Get the full article here.  Neat stuff.  Here’s the full citation:

Discovery of a hepatitis C target and its pharmacological inhibitors by microfluidic affinity analysis

Shirit Einav, Doron Gerber, Paul D Bryson, Ella H Sklan, Menashe Elazar, Sebastian J Maerkl, Jeffrey S Glenn & Stephen R Quake

Nature Biotechnology. Published online: 31 August 2008; | doi:10.1038

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